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1

Control of the p53 response

Nicholas B. La Thangue

Journal:

Year:

2007

Language:

english

File:

PDF, 48 KB

english, 2007

2

10.1038/35008660

La Thangue, Nicholas B., Morris, Lorna, Allen, K. Elizabeth

Journal:

Nature Cell Biology

Year:

2000

Language:

english

File:

PDF, 333 KB

english, 2000

3

10.1038/35083062

Chan, Ho Man, Krstic-Demonacos, Marija, Smith, Linda, Demonacos, Constantinos, Thangue, Nicholas B. La

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 492 KB

english, 2001

4

Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor

Bandara, Lasantha R., La Thangue, Nicholas B.

Journal:

Year:

1991

File:

PDF, 444 KB

1991

5

Cyclin A and the retinoblastoma gene product complex with a common transcription factor

Bandara, Lasantha R., Adamczewski, Jörg P., Hunt, Tim, La Thangue, Nicholas B.

Journal:

Year:

1991

File:

PDF, 473 KB

1991

6

A new component of the transcription factor DRTF1/E2F

Girling, Rowena, Partridge, Janet F., Bandara, Lasantha R., Burden, Neil, Totty, Nicholas F., Hsuan, J. Justin, Thangue, Nicholas B. La

Journal:

Year:

1993

File:

PDF, 688 KB

1993

7

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

Martin, Klaus, Trouche, Didier, Hagemeier, Christian, Sorensen, Troels S., La Thangue, Nicholas B., Kouzarides, Tony

Journal:

Year:

1995

File:

PDF, 424 KB

1995

8

Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein

Carr, Simon M, Munro, Shonagh, Kessler, Benedikt, Oppermann, Udo, La Thangue, Nicholas B

Journal:

The EMBO Journal

Year:

2010

Language:

english

File:

PDF, 1.49 MB

english, 2010

9

ATM and Chk2 kinase target the p53 cofactor Strap

Adams, Cassandra J, Graham, Anne L, Jansson, Martin, Coutts, Amanda S, Edelmann, Mariola, Smith, Linda, Kessler, Benedikt, La Thangue, Nicholas B

Journal:

Year:

2008

Language:

english

File:

PDF, 592 KB

english, 2008

10

A transcription cofactor required for the heat-shock response

Xu, Danmei, Zalmas, L Panagiotis, La Thangue, Nicholas B

Journal:

Year:

2008

Language:

english

File:

PDF, 278 KB

english, 2008

11

Apoptosis induced in mammalian cells by small peptides that functionally antagonize the Rb-regulated E2F transcription factor

Bandara, Lasantha R., Girling, Rowena, Thangue, Nicholas B. La

Journal:

Nature Biotechnology

Year:

1997

File:

PDF, 874 KB

1997

12

A mismatched role for Bcl-2

La Thangue, Nicholas B.

Journal:

Nature Cell Biology

Year:

2005

Language:

english

File:

PDF, 126 KB

english, 2005

13

The yin and yang of E2F-1: balancing life and death

La Thangue, Nicholas B.

Journal:

Nature Cell Biology

Year:

2003

Language:

english

File:

PDF, 105 KB

english, 2003

14

A new effector pathway links ATM kinase with the DNA damage response

Demonacos, Constantinos, Krstic-Demonacos, Marija, Smith, Linda, Xu, Danmei, O'Connor, Darran P., Jansson, Martin, Thangue, Nicholas B. La

Journal:

Nature Cell Biology

Year:

2004

Language:

english

File:

PDF, 1.42 MB

english, 2004

15

Arginine methylation regulates the p53 response

Jansson, Martin, Durant, Stephen T., Cho, Er-Chieh, Sheahan, Sharon, Edelmann, Mariola, Kessler, Benedikt, La Thangue, Nicholas B.

Journal:

Nature Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.83 MB

english, 2008

16

Chk2 activates E2F-1 in response to DNA damage

Stevens, Craig, Smith, Linda, La Thangue, Nicholas B.

Journal:

Nature Cell Biology

Year:

2003

Language:

english

File:

PDF, 2.00 MB

english, 2003

17

14-3-3 proteins integrate E2F activity with the DNA damage response

Milton, Alasdair H, Khaire, Nandkumar, Ingram, Laura, O'donnell, Amanda J, La Thangue, Nicholas B

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 357 KB

english, 2006

18

DNA-damage-responsive acetylation of pRb regulates binding to E2F-1

Markham, Douglas, Munro, Shonagh, Soloway, Judith, O'Connor, Darran P, La Thangue, Nicholas B

Journal:

Year:

2006

Language:

english

File:

PDF, 209 KB

english, 2006

19

Mdm2 targets the p53 transcription cofactor JMY for degradation

Coutts, Amanda S, Boulahbel, Houda, Graham, Anne, La Thangue, Nicholas B

Journal:

Year:

2006

Language:

english

File:

PDF, 206 KB

english, 2006

20

DNA-damage response control of E2F7 and E2F8

Panagiotis Zalmas, L, Zhao, Xiujie, Graham, Anne L, Fisher, Rebecca, Reilly, Carmel, Coutts, Amanda S, La Thangue, Nicholas B

Journal:

Year:

2008

Language:

english

File:

PDF, 333 KB

english, 2008

21

Functional interplay between p53 and E2F through co-activator p300

Lee, Chang-Woo, Sørensen, Troels S, Shikama, Noriko, Thangue, Nicholas B La

Journal:

Year:

1998

Language:

english

File:

PDF, 571 KB

english, 1998

22

Promoter specificity and stability control of the p53-related protein p73

Lee, Chang-Woo, La Thangue, Nicholas B

Journal:

Year:

1999

Language:

english

File:

PDF, 451 KB

english, 1999

23

Control of E2F activity by p21Waf1/Cip1

Delavaine, Laurent, La Thangue, Nicholas B

Journal:

Year:

1999

Language:

english

File:

PDF, 503 KB

english, 1999

24

Role of LXCXE motif-dependent interactions in the activity of the retinoblastoma protein

Chan, Ho Man, Smith, Linda, La Thangue, Nicholas B

Journal:

Year:

2001

Language:

english

File:

PDF, 503 KB

english, 2001

25

p14ARF regulates E2F activity

Mason, Sarah L, Loughran, &#214, onagh, La Thangue, Nicholas B

Journal:

Year:

2002

Language:

english

File:

PDF, 383 KB

english, 2002

26

E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains

Logan, Nicola, Delavaine, Laurent, Graham, Anne, Reilly, Carmel, Wilson, Jon, Brummelkamp, Thijn R, Hijmans, E Marielle, Bernards, René, La Thangue, Nicholas B

Journal:

Year:

2004

Language:

english

File:

PDF, 620 KB

english, 2004

27

E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7

Logan, Nicola, Graham, Anne, Zhao, Xuijie, Fisher, Rebecca, Maiti, Baidehi, Leone, Gustavo, Thangue, Nicholas B La

Journal:

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

28

Predictive biomarkers: a paradigm shift towards personalized cancer medicine

La Thangue, Nicholas B., Kerr, David J.

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2011

Language:

english

File:

PDF, 653 KB

english, 2011

29

Introduction: Cell cycle regulation and cancer

Nicholas B. La Thangue

Journal:

Seminars in Cancer Biology

Year:

1995

Language:

english

File:

PDF, 17 KB

english, 1995

30

A structural similarity between mammalian and yeast transcription factors for cell-cycle-regulated genes

Nicholas B. La Thangue, William R. Taylor

Journal:

Trends in Cell Biology

Year:

1993

Language:

english

File:

PDF, 611 KB

english, 1993

31

Histone deacetylase inhibitors open new doors in cancer therapy

Fiona McLaughlin, Nicholas B La Thangue

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 198 KB

english, 2004

32

Genome-wide Loss-of-Function Screen Reveals an Important Role for the Proteasome in HDAC Inhibitor-Induced Apoptosis

Susan Fotheringham, Mirjam T. Epping, Lindsay Stimson, Omar Khan, Victoria Wood, Francesco Pezzella, René Bernards, Nicholas B. La Thangue

Journal:

Year:

2009

Language:

english

File:

PDF, 1.46 MB

english, 2009

33

E2F proteins

Öonagh Loughran, Nicholas B La Thangue

Journal:

Current Biology

Year:

2002

Language:

english

File:

PDF, 196 KB

english, 2002

34

Chromatin research gathers pace

Jonathan Lyon, Nicholas B. La Thangue

Journal:

Trends in Cell Biology

Year:

1997

Language:

english

File:

PDF, 128 KB

english, 1997

35

The cell cycle, chromatin and cancer: mechanism-based therapeutics come of age

Fiona McLaughlin, Paul Finn, Nicholas B La Thangue

Journal:

Drug Discovery Today

Year:

2003

Language:

english

File:

PDF, 203 KB

english, 2003

36

Keynote review: Chromatin control and cancer-drug discovery: realizing the promise

Adam G. Inche, Nicholas B. La Thangue

Journal:

Drug Discovery Today

Year:

2006

Language:

english

File:

PDF, 1.90 MB

english, 2006

37

The cell cycle and drug discovery: the promise and the hope

Gavin Brooks, Nicholas B La Thangue

Journal:

Drug Discovery Today

Year:

1999

Language:

english

File:

PDF, 205 KB

english, 1999

38

T-ARG-eting E2F-1 growth control

Moehlenbrink, Jutta, La Thangue, Nicholas B.

Journal:

Year:

2012

Language:

english

File:

PDF, 484 KB

english, 2012

39

A cellular protein related to heat-shock protein 90 accumulates during herpes simplex virus infection and is overexpressed in transformed cells

Nicholas B.La Thangue, David S. Latchman

Journal:

Experimental Cell Research

Year:

1988

Language:

english

File:

PDF, 2.63 MB

english, 1988

40

The p53 response: Emerging levels of co-factor complexity

Amanda S. Coutts, Nicholas B. La Thangue

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 282 KB

english, 2005

41

Biomarkers for predicting clinical responses to HDAC inhibitors

Lindsay Stimson, Nicholas B. La Thangue

Journal:

Year:

2009

Language:

english

File:

PDF, 268 KB

english, 2009

42

Histone deacetylase inhibitors: gathering pace

Nessa Carey, Nicholas B La Thangue

Journal:

Current Opinion in Pharmacology

Year:

2006

Language:

english

File:

PDF, 166 KB

english, 2006

43

The emerging role of E2F-1 in the DNA damage response and checkpoint control

Craig Stevens, Nicholas B. La Thangue

Journal:

Year:

2004

Language:

english

File:

PDF, 235 KB

english, 2004

44

E2F and cell cycle control: a double-edged sword

Craig Stevens, Nicholas B La Thangue

Journal:

Archives of Biochemistry and Biophysics

Year:

2003

Language:

english

File:

PDF, 275 KB

english, 2003

45

A Novel Cofactor for p300 that Regulates the p53 Response

Noriko Shikama, Chang-Woo Lee, Stephen France, Laurent Delavaine, Jonathan Lyon, Marija Krstic-Demonacos, Nicholas B La Thangue

Journal:

Year:

1999

Language:

english

File:

PDF, 480 KB

english, 1999

46

A TPR Motif Cofactor Contributes to p300 Activity in the p53 Response

Constantinos Demonacos, Marija Krstic-Demonacos, Nicholas B La Thangue

Journal:

Year:

2001

Language:

english

File:

PDF, 653 KB

english, 2001

47

An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells

Nicholas B. La Thangue, Peter W.J. Rigby

Journal:

Year:

1987

Language:

english

File:

PDF, 1.79 MB

english, 1987

48

p53 ubiquitination by Mdm2: A never ending tail?

Amanda S. Coutts, Cassandra J. Adams, Nicholas B. La Thangue

Journal:

Year:

2009

Language:

english

File:

PDF, 415 KB

english, 2009

49

p53-cofactor JMY is a multifunctional actin nucleation factor

Zuchero, J. Bradley, Coutts, Amanda S., Quinlan, Margot E., Thangue, Nicholas B. La, Mullins, R. Dyche

Journal:

Nature Cell Biology

Year:

2009

Language:

english

File:

PDF, 3.34 MB

english, 2009

50

HDAC inhibitor-based therapies: Can we interpret the code?

New, Maria, Olzscha, Heidi, La Thangue, Nicholas B.

Journal:

Molecular Oncology

Year:

2012

Language:

english

File:

PDF, 803 KB

english, 2012

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